Ethyl 2-(2-methyl-1H-benzimidazol-1-yl)acetate

نویسندگان

  • Guang-Hai Xu
  • Wei Wang
چکیده

A new benzimidazole compound, C(12)H(14)N(2)O(2), has been synthesized by the reaction of 2-methyl-1H-benzimidazole and ethyl 2-bromo-acetate. In the crystal structure, weak inter-molecular C-H⋯N hydrogen bonds link the mol-ecules into chains. π⋯π Contacts (centroid⋯centroid distance = 3.713 Å) are observed. A C-H⋯π inter-action is also present. The N-C-C-O torsion angle is 178.4 (2)°.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Synthesis and biological evaluation of some novel 2-phenyl benzimidazole-1-acetamide derivatives as potential anthelmintic agents.

The present study describes synthesis of a series of 2-phenyl benzimidazole-1-acetamide derivatives and their evaluation for anthelmintic activity using Indian adult earthworms, Pheretima posthuma. The structure of the title compounds was elucidated by elemental analysis and spectral data. The compounds 4-({[2-(4-nitrophenyl)-1H-benzimidazol-1-yl]acetyl}amino) benzoic acid (3a), N-ethyl-2-[2-(4...

متن کامل

Crystal structure of ethyl 2-(1H-benzimidazol-2-yl)-2-[2-(4-nitro­phen­yl)hydrazinyl­idene]acetate

The title compound, C17H15N5O4, was obtained via the condensation of 3-eth-oxy-2-[2-(4-nitro-phen-yl)hydrazono]-3-oxo-propanoic acid with 1,2-di-amino-benzene. In the mol-ecule, the dihedral angles between the acetate group and the two aromatic subunits (benzimidazole and nitro-phenyl-hydrazone) are 7.35 (9) and 18.23 (9)°, respectively. Intra-molecular N-H⋯O and N-H⋯N contacts occur. In the cr...

متن کامل

N-Paranitrophénylhydrazono-α-(2-méthyl­benzimidazol-1-yl)glyoxylate d’éthyle

There are two independent mol-ecules in the asymmetric unit of the title compound {systematic name: ethyl 2-(2-methyl-1H-benzimidazol-1-yl)-2-[2-(4-nitro-phen-yl)hydrazinyl-idene]ethano-ate}, C(18)H(17)N(5)O(4). Each mol-ecule and its inversion-related partner are linked by a pair of inter-molecular N-H⋯N hydrogen bonds, forming inversion dimers in the crystal structure.

متن کامل

Crystal structure of azilsartan methyl ester ethyl acetate hemisolvate

The title compound, C26H22N4O5 (systematic name: methyl 2-eth-oxy-1-{4-[2-(5-oxo-4,5-di-hydro-1,2,4-oxa-diazol-3-yl)phenyl]benz-yl}-1H-1,3-benzo-diazole-7-carboxyl-ate ethyl acetate hemisolvate), was obtained via cyclization of methyl (Z)-2-eth-oxy-1-{(2'-(N'-hy-droxy-carbamimido-yl)-[1,1'-biphen-yl]-4-yl)meth-yl}-1H-benzo[d]imidazole-7-carboxyl-ate with diphen-yl carbonate. There are two indep...

متن کامل

Ethyl (E)-1-(2-styryl-1H-benzimidazol-1-yl)acetate

In the title compound, C(19)H(18)NO(2), the dihedral angle between the benzimidazole and phenyl ring planes is 18.18 (17)°. The atoms of the ethyl side chain are disordered over two sets of sites in a 0.50:0.50 ratio. In the crystal, inter-molecular C-H⋯O hydrogen bonds and C-H⋯π contacts help to consolidate the packing.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 64  شماره 

صفحات  -

تاریخ انتشار 2008